Hitzel, Laure : rechercher sur Z-Library

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1

4-Substituted cyclohexyl sulfones as potent, orally active γ-secretase inhibitors

Ian Churcher, Dirk Beher, Jonathan D. Best, José L. Castro, Earl E. Clarke, Amy Gentry, Timothy Harrison, Laure Hitzel, Euan Kay, Sonia Kerrad, Huw D. Lewis, Pablo Morentin-Gutierrez, Russell Mortishi

Journal:

Bioorganic & Medicinal Chemistry Letters

Année:

2006

Langue:

english

Fichier:

PDF, 168 KB

english, 2006

2

Prediction of retention for sulfonamides in supercritical fluid chromatography

Amaury Cazenave-Gassiot, Robert Boughtflower, Jeffrey Caldwell, Richard Coxhead, Laure Hitzel, Stephen Lane, Paul Oakley, Clare Holyoak, Frank Pullen, G. John Langley

Journal:

Journal of Chromatography A

Année:

2008

Langue:

english

Fichier:

PDF, 389 KB

english, 2008

3

Effect of increasing concentration of ammonium acetate as an additive in supercritical fluid chromatography using CO2–methanol mobile phase

Amaury Cazenave-Gassiot, Robert Boughtflower, Jeffrey Caldwell, Laure Hitzel, Claire Holyoak, Stephen Lane, Paul Oakley, Frank Pullen, Stefan Richardson, G. John Langley

Journal:

Journal of Chromatography A

Année:

2009

Langue:

english

Fichier:

PDF, 1.26 MB

english, 2009

4

Selectivity optimization in green chromatography by gradient stationary phase optimized selectivity liquid chromatography

Kai Chen, Frédéric Lynen, Maarten De Beer, Laure Hitzel, Paul Ferguson, Melissa Hanna-Brown, Pat Sandra

Journal:

Journal of Chromatography A

Année:

2010

Langue:

english

Fichier:

PDF, 620 KB

english, 2010

5

Use of chiral liquid chromatography–tandem mass spectrometry to investigate the metabolism of racemic cholecystokinin-B antagonists

Alan P Watt, Laure Hitzel, Denise Morrison, Karen L Locker

Journal:

Journal of Chromatography A

Année:

2000

Langue:

english

Fichier:

PDF, 1.37 MB

english, 2000

6

Determination of the in vitro metabolism of (+)- and (−)-epibatidine

Alan P Watt, Laure Hitzel, Denise Morrison, Karen L Locker

Journal:

Journal of Chromatography A

Année:

2000

Langue:

english

Fichier:

PDF, 360 KB

english, 2000

7

Parallel synthesis of 3-aryloxy-2-propanolamines and evaluation as dual affinity 5-HT1A and 5-HT re-uptake ligands

Monique B. van Niel, Margaret S. Beer, JoséL. Castro, Susan K.F. Cheng, David C. Evans, Anne Heald, Laure Hitzel, Peter Hunt, Russell Mortishire-Smith, Desmond O'Connor, Alan P. Watt, Angus M. MacLeod

Journal:

Bioorganic & Medicinal Chemistry Letters

Année:

1999

Langue:

english

Fichier:

PDF, 321 KB

english, 1999

8

Ionisation in the absence of high voltage using supercritical fluid chromatography: a possible route to increased signal

Mohini A. Thite, Robert Boughtflower, Jeff Caldwell, Laure Hitzel, Clare Holyoak, Stephen J. Lane, Paul Oakley, Frank S. Pullen, Stefan Richardson, G. John Langley

Journal:

Rapid Communications in Mass Spectrometry

Année:

2008

Langue:

english

Fichier:

PDF, 366 KB

english, 2008

9

An Increased Throughput Method for the Determination of Partition Coefficients

Laure Hitzel, Alan P Watt, Karen L Locker

Journal:

Pharmaceutical Research

Année:

2000

Langue:

english

Fichier:

PDF, 192 KB

english, 2000

10

Lead Diversification 2: Application to P38, gMTP and lead compounds

M. Abid Masood, Marc Bazin, Mark E. Bunnage, Andrew Calabrese, Mark Cox, Sally-Ann Fancy, Elizabeth Farrant, David W. Pearce, Manuel Perez, Laure Hitzel, Torren Peakman

Journal:

Bioorganic & Medicinal Chemistry Letters

Année:

2012

Langue:

english

Fichier:

PDF, 668 KB

english, 2012

11

Neighboring Group Participation of the Indole Nucleus: An Unusual DAST-Mediated Rearrangement Reaction

Hallett, David J., Gerhard, Ute, Goodacre, Simon C., Hitzel, Laure, Sparey, Timothy J., Thomas, Steven, Rowley, Michael, Ball, Richard G.

Journal:

Journal of Organic Chemistry

Année:

2000

Langue:

english

Fichier:

PDF, 205 KB

english, 2000

12

Enantiomeric separation of substituted 2-arylindoles on derivatised polysaccharide chiral stationary phases

Alan P. Watt, Laure Hitzel, Russell J. Mortishire-Smith

Journal:

Journal of Biochemical and Biophysical Methods

Année:

2002

Langue:

english

Fichier:

PDF, 178 KB

english, 2002

13

3-[3-(Piperidin-1-yl)propyl]indoles as Highly Selective h5-HT 1D Receptor Agonists

Russell, Michael G. N., Matassa, Victor G., Pengilley, Roy R., van Niel, Monique B., Sohal, Bindi, Watt, Alan P., Hitzel, Laure, Beer, Margaret S., Stanton, Josephine A., Broughton, Howard B., Castro,

Journal:

Journal of Medicinal Chemistry

Année:

1999

Langue:

english

Fichier:

PDF, 766 KB

english, 1999

14

Synthesis and Conformational Dynamics of Tricyclic Pyridones Containing a Fused Seven-Membered Ring

Gibson, Karl R., Hitzel, Laure, Mortishire-Smith, Russell J., Gerhard, Ute, Jelley, Richard A., Reeve, Austin J., Rowley, Michael, Nadin, Alan, Owens, Andrew P.

Journal:

Journal of Organic Chemistry

Année:

2002

Langue:

english

Fichier:

PDF, 179 KB

english, 2002

15

A New Strategy for Fast Chiral Screening by Combining HPLC-DAD with a Multivariate Curve Resolution–Alternating Least Squares Algorithm

Kai Chen, Frédéric Lynen, Laure Hitzel, Melissa Hanna-Brown, Roman Szucs, Pat Sandra

Journal:

Chromatographia

Année:

2013

Langue:

english

Fichier:

PDF, 433 KB

english, 2013

16

An Efficient Protocol for the Preparation of Primary Alcohols Bearing a β-Chiral Center via an Oxazolidinone Auxiliary Mediated Resolution, and Application to the Synthesis of 4,4-Disubstituted Piperidine Substance P Antagonists

Lewis, Richard T., Ladduwahetty, Tamara, Merchant, Kevin J., Keown, Linda E., Hitzel, Laure, Verrier, Hugh, Stevenson, Graeme I., MacLeod, Angus M.

Journal:

Journal of Organic Chemistry

Année:

2000

Langue:

english

Fichier:

PDF, 77 KB

english, 2000

17

CHIRAL SEPARATION OF 4,4-DISUBSTITUTED PIPERIDINYL SUBSTANCE P ANTAGONISTS

Watt, Alan P., Hitzel, Laure

Journal:

Journal of Liquid Chromatography & Related Technologies

Année:

2000

Langue:

english

Fichier:

PDF, 173 KB

english, 2000

18

A concise synthesis of chiral indanes as α1A adrenoceptor partial agonists

Roberts, Lee R., Corbett, Matthew S., Fussell, Steven J., Hitzel, Laure, Jessiman, Alan S., Mason, Helen J., Osborne, Rachel, Ralph, Michael J., Stennett, Adam S.D., Wheeler, Simon, Storer, R. Ian

Journal:

Tetrahedron Letters

Année:

2015

Langue:

english

Fichier:

PDF, 2.35 MB

english, 2015

19

Cortical florbetapir-PET amyloid load in prodromal Alzheimer’s disease patients

Saint-Aubert, Laure, Barbeau, Emmanuel J, Péran, Patrice, Nemmi, Federico, Vervueren, Celine, Mirabel, Helene, Payoux, Pierre, Hitzel, Anne, Bonneville, Fabrice, Gramada, Raluca, Tafani, Mathieu, Vinc

Journal:

EJNMMI Research

Année:

2013

Langue:

english

Fichier:

PDF, 574 KB

english, 2013

20

Amyloid Imaging with AV45 (18F-florbetapir) in a Cognitively Normal AβPP Duplication Carrier

Saint-Aubert, Laure, Planton, Mélanie, Hannequin, Didier, Albucher, Jean-François, Delisle, Marie-Bernadette, Payoux, Pierre, Hitzel, Anne, Viallard, Gérard, Péran, Patrice, Campion, Dominique, Laquer

Journal:

Journal of Alzheimer's Disease

Année:

2012

Langue:

english

Fichier:

PDF, 514 KB

english, 2012

21

Weight-loss with activation of brown fat: suspect pheochromocytoma

Geslot, Aurore, Bennet, Antoine, Hitzel, Anne, Thoulouzan, Matthieu, Mouly, Céline, Savagner, Frédérique, Quintyn-Ranty, Marie-Laure, Caron, Philippe, Vezzosi, Delphine

Journal:

Annales d'Endocrinologie

Année:

2019

Fichier:

PDF, 300 KB

2019

22

Weight-loss with activation of brown fat: suspect pheochromocytoma

Geslot, Aurore, Bennet, Antoine, Hitzel, Anne, Thoulouzan, Matthieu, Mouly, Céline, Savagner, Frédérique, Quintyn-Ranty, Marie-Laure, Caron, Philippe, Vezzosi, Delphine

Journal:

Annales d'Endocrinologie

Année:

2019

Fichier:

PDF, 300 KB

2019